Mike Clay is a senior writer for fantasy football and the NFL at ESPN. Week 1 of the 2025 NFL season is around the corner. Below is a guide of what to expect once the season kicks off Thursday — including power rankings of all 32 teams, a list of teams that will score the most points and defenses that will allow the fewest, and a look at the toughest and easiest schedules. If you’re looking for even more in-depth content, check my rankings and assessments of the best and worst positional units across the league, as well as my 80-page projections PDF.