The Pittsburgh Pirates made changes to their lineup for the series finale vs. the Chicago Cubs at Wrigley Field, including having one of their best players at a different position. Bryan Reynolds will serve as the designated hitter for the Pirates, with Andrew McCutchen not starting, and will bat second. This marks the 18th start for Reynolds at designated hitter, last doing so in the series opener vs. the Philadelphia Phillies at PNC Park on June 6.