The San Francisco 49ers have experienced some injury woes ahead of the 2025-26 campaign, especially in the wide receiver room. On Wednesday, head coach Kyle Shanahan shared an optimistic update regarding the defensive line. With Dominick Puni and Yetur Gross-Matos both dealing with knee injuries, Shanahan claims that both players will be ready to go by the Week 1 opener against the Seattle Seahawks, according to Matt Barrows of The Athletic.