The San Francisco 49ers have had a bumpy offseason. The 49ers placed Aiyuk on the physically unable to perform list, which means he’ll be inactive for at least the first four games of the season before being allowed to return to practice. San Francisco head coach Kyle Shanahan has already said this month that Week 6 might be a logical return date for Aiyuk. Aiyuk was injured in Week 7 last year, when he tore both his MCL and ACL.